Annexin A2 Protein (ANXA2) (AA 2-339)

Catalog No. ABIN1096014

Product Details

Target: Annexin A2 (ANXA2)

Protein Type: Recombinant

Protein Characteristics: AA 2-339

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Annexin A2/ANXA2

Sequence: MSTVHEILCK LSLEGDHSTP PSAYGSVKAY TNFDAERDAL NIETAIKTKG VDEVTIVNIL TNRSNAQRQD IAFAYQRRTK KELASALKSA LSGHLETVIL GLLKTPAQYD ASELKASMKG LGTDEDSLIE IICSRTNQEL QEINRVYKEM YKTDLEKDII SDTSGDFRKL MVALAKGRRA EDGSVIDYEL IDQDARDLYD AGVKRKGTDV PKWISIMTER SVPHLQKVFD RYKSYSPYDM LESIRKEVKG DLENAFLNLV QCIQNKPLYF ADRLYDSMKG KGTRDKVLIR IMVSRSEVDM LKIRSEFKRK YGKSLYYYIQ QDTKGDYQKA LLYLCGGDD

Characteristics: Recombinant Human Annexin A2/ANXA2 is produced by our E. coli expression system. The target protein is expressed with sequence (Ser2-Asp339) of Human ANXA2.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM EDTA, pH 7.5 .

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Annexin A2 (ANXA2)

Alternative Name: annexin-a2 (ANXA2 Products)

Synonyms: ANX2 Protein, ANX2L4 Protein, CAL1H Protein, LIP2 Protein, LPC2 Protein, LPC2D Protein, P36 Protein, PAP-IV Protein, AW215814 Protein, Cal1h Protein, p36 Protein, anx2 Protein, lip2 Protein, lpc2 Protein, cal1h Protein, lpc2d Protein, pap-i Protein, anx2l4 Protein, MGC76145 Protein, ANXA2 Protein, anxa2 Protein, anxa2-a Protein, anxa2-b Protein, annexin A2 Protein, annexin A2 S homeolog Protein, ANXA2 Protein, Anxa2 Protein, anxa2 Protein, anxa2.S Protein

Background: Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell differentiation.
Alternative Names: Annexin A2, Annexin II, Annexin-2, Calpactin I Heavy Chain, Calpactin-1 Heavy Chain, Chromobindin-8, Lipocortin II, Placental Anticoagulant Protein IV, PAP-IV, Protein I, p36, ANXA2, ANX2, ANX2L4, CAL1H, LPC2D

Molecular Weight: 38.6 kDa

UniProt: P07355

Pathways: S100 Proteins