CA4 Protein (AA 19-283) (His tag)

Catalog No. ABIN1096197

Product Details

Target: CA4 (Carbonic Anhydrase IV (CA4))

Protein Type: Recombinant

Protein Characteristics: AA 19-283

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CA4 protein is labelled with His tag.

Purpose: Recombinant Human Carbonic Anhydrase 4/CA4 (C-6His)

Sequence: MAESHWCYEV QAESSNYPCL VPVKWGGNCQ KDRQSPINIV TTKAKVDKKL GRFFFSGYDK KQTWTVQNNG HSVMMLLENK ASISGGGLPA PYQAKQLHLH WSDLPYKGSE HSLDGEHFAM EMHIVHEKEK GTSRNVKEAQ DPEDEIAVLA FLVEAGTQVN EGFQPLVEAL SNIPKPEMST TMAESSLLDL LPKEEKLRHY FRYLGSLTTP TCDEKVVWTV FREPIQLHRE QILAFSQKLY YDKEQTVSMK DNVRPLQQLG QRTVIKLEHH HHHH

Characteristics: Recombinant Human Carbonic Anhydrase 4/CA4 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala19-Lys283) of Human CA4.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, pH 8.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: CA4 (Carbonic Anhydrase IV (CA4))

Alternative Name: Carbonic Anhydrase 4/CA4 (CA4 Products)

Synonyms: CAIV Protein, Car4 Protein, RP17 Protein, AW456718 Protein, Ca4 Protein, ca4 Protein, caiv Protein, car4 Protein, rp17 Protein, CA4 Protein, zgc:171842 Protein, carbonic anhydrase 4 Protein, carbonic anhydrase 4 S homeolog Protein, carbonic anhydrase IV a Protein, CA4 Protein, Car4 Protein, ca4 Protein, ca4.S Protein, Ca4 Protein, ca4a Protein

Background: Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris.
Alternative Names: Carbonic Anhydrase 4, Carbonate Dehydratase IV, Carbonic Anhydrase IV, CA-IV, CA4

Molecular Weight: 31.43 kDa

UniProt: P22748