Cathepsin S Protein (CTSS) (AA 17-331) (His tag)
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- Target See all Cathepsin S (CTSS) Proteins
- Cathepsin S (CTSS)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-331
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Cathepsin S protein is labelled with His tag.
- Purpose
- Recombinant Human Cathepsin S/CTSS (C-6His)
- Sequence
- QLHKDPTLDH HWHLWKKTYG KQYKEKNEEA VRRLIWEKNL KFVMLHNLEH SMGMHSYDLG MNHLGDMTSE EVMSLMSSLR VPSQWQRNIT YKSNPNWILP DSVDWREKGC VTEVKYQGSC GACWAFSAVG ALEAQLKLKT GKLVSLSAQN LVDCSTEKYG NKGCNGGFMT TAFQYIIDNK GIDSDASYPY KAMDQKCQYD SKYRAATCSK YTELPYGRED VLKEAVANKG PVSVGVDARH PSFFLYRSGV YYEPSCTQNV NHGVLVVGYG DLNGKEYWLV KNSWGHNFGE EGYIRMARNK GNHCGIASFP SYPEIVDHHH HHH
- Characteristics
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Recombinant Human Cathepsin S/CTSS (C-6His)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CTSS Protein
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Cathepsin S (CTSS) (AA 1-331) protein (GST tag)
CTSS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin S (CTSS) protein (His tag)CTSS Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin S (CTSS) (Active) protein (His tag)CTSS Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Cathepsin S (CTSS) (AA 115-331) protein (His tag)Crystallography grade CTSS Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cathepsin S (CTSS) (AA 123-340) protein (His tag)Crystallography grade CTSS Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, 10 % Glycerol, pH 5.5.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- Cathepsin S (CTSS)
- Alternative Name
- Cathepsin S (CTSS Products)
- Synonyms
- ctss-a Protein, MGC69026 Protein, ctss-b Protein, MGC80097 Protein, ctss.1 Protein, CTSS Protein, ctss Protein, cats Protein, cathepsin S Protein, cathepsin S L homeolog Protein, cathepsin S S homeolog Protein, Cathepsin S Protein, CTSS Protein, Ctss Protein, ctss.L Protein, ctss.S Protein, ctss Protein, cats Protein
- Background
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Recombinant Human Cathepsin S is produced with our mammalian expression system in human cells. The target protein is expressed with the full length sequence of Human CTSS fused with a polyhistidine tag at the C-terminus.
Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A β from amyloidogenic fragments of β APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS). - Molecular Weight
- 36.89 kDa
- UniProt
- P25774
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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