CEACAM3 Protein (AA 35-155) (His tag)

Catalog No. ABIN1096368

Product Details

Target: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Protein Type: Recombinant

Protein Characteristics: AA 35-155

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CEACAM3 protein is labelled with His tag.

Purpose: Recombinant Human CEACAM3/CD66d (C-6His)

Sequence: KLTIESMPLS VAEGKEVLLL VHNLPQHLFG YSWYKGERVD GNSLIVGYVI GTQQATPGAA YSGRETIYTN ASLLIQNVTQ NDIGFYTLQV IKSDLVNEEA TGQFHVYQEN APGLPVGAVA GVDHHHHHH

Characteristics: Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3/CEACAM3 produced by transfected human cells is a secreted protein with sequence (K35-G155) of Human CEACAM3 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Alternative Name: cd66d (CEACAM3 Products)

Synonyms: CD66D Protein, CEA Protein, CGM1 Protein, W264 Protein, W282 Protein, CGM4AA Protein, Cea Protein, Ceacam5 Protein, Cear Protein, Cgm1 Protein, Cgm4 Protein, RATCEAA Protein, RATCGM4AA Protein, EG384557 Protein, Psg24 Protein, cea12 Protein, carcinoembryonic antigen related cell adhesion molecule 3 Protein, carcinoembryonic antigen-related cell adhesion molecule 3 Protein, CEACAM3 Protein, Ceacam3 Protein

Sub Type: Fusionprotein

Background: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3) belongs to the immunoglobulin superfamily and CEA family. CEACAM3 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM3 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, it is associated with the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
Alternative Names: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3, Carcinoembryonic Antigen CGM1, CD66d, CEACAM3, CD66D, CGM1

Molecular Weight: 14.13 kDa

UniProt: P40198