CLIC5 Protein (AA 1-251) (His tag)

Catalog No. ABIN1096410

Product Details

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Protein Type: Recombinant

Protein Characteristics: AA 1-251

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CLIC5 protein is labelled with His tag.

Purpose: Recombinant Human Chloride Intracellular Channel Protein 5/CLIC5 (N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MTDSATANGD DRDPEIELFV KAGIDGESIG NCPFSQRLFM ILWLKGVVFN VTTVDLKRKP ADLHNLAPGT HPPFLTFNGD VKTDVNKIEE FLEETLTPEK YPKLAAKHRE SNTAGIDIFS KFSAYIKNTK QQNNAALERG LTKALKKLDD YLNTPLPEEI DANTCGEDKG SRRKFLDGDE LTLADCNLLP KLHVVKIVAK KYRNYDIPAE MTGLWRYLKN AYARDEFTNT CAADSEIELA YADVAKRLSR S

Characteristics: Recombinant Human Chloride Intracellular Channel Protein 5/CLIC5 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser251) of Human CLIC5 fused with a His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Alternative Name: CLIC5 (CLIC5 Products)

Synonyms: MST130 Protein, MSTP130 Protein, 5730531E12Rik Protein, B330005L24 Protein, Gm322 Protein, jbg Protein, clic5 Protein, im:6907594 Protein, zgc:77538 Protein, CLIC5 Protein, zgc:101827 Protein, chloride intracellular channel 5 Protein, chloride intracellular channel 5b Protein, chloride intracellular channel 5a Protein, chloride intracellular channel 5 L homeolog Protein, CLIC5 Protein, Clic5 Protein, clic5b Protein, clic5a Protein, clic5.L Protein

Sub Type: Fusionprotein

Background: Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specifically associates with the cytoskeleton of placenta microvilli. CLIC5 is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture.
Alternative Names: Chloride Intracellular Channel Protein 5, CLIC5

Molecular Weight: 30.3 kDa

UniProt: Q9NZA1

Pathways: Sensory Perception of Sound