GGCT Protein (AA 1-188) (His tag)
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- Target See all GGCT Proteins
- GGCT (gamma-Glutamylcyclotransferase (GGCT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-188
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GGCT protein is labelled with His tag.
- Purpose
- Recombinant Human γ-Glutamylcyclotransferase/GGCT (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MANSGCKDVT GPDEESFLYF AYGSNLLTER IHLRNPSAAF FCVARLQDFK LDFGNSQGKT SQTWHGGIAT IFQSPGDEVW GVVWKMNKSN LNSLDEQEGV KSGMYVVIEV KVATQEGKEI TCRSYLMTNY ESAPPSPQYK KIICMGAKEN GLPLEYQEKL KAIEPNDYTG KVSEEIEDII KKGETQTL
- Characteristics
- Recombinant Human gamma-Glutamylcyclotransferase/GGCT is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Leu188) of Human GGCT fused with a His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product GGCT Protein
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gamma-Glutamylcyclotransferase (GGCT) (AA 1-188) protein (His tag)
GGCT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
gamma-Glutamylcyclotransferase (GGCT) (AA 1-188) protein (Strep Tag)Crystallography grade GGCT Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
gamma-Glutamylcyclotransferase (GGCT) (AA 1-188), (full length) protein (His-SUMO Tag)GGCT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
gamma-Glutamylcyclotransferase (GGCT) protein (Myc-DYKDDDDK Tag)GGCT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- GGCT (gamma-Glutamylcyclotransferase (GGCT))
- Alternative Name
- CRF21 (GGCT Products)
- Synonyms
- fj35c05 Protein, ggct Protein, wu:fj35b07 Protein, wu:fj35c05 Protein, zgc:56140 Protein, A030007L17Rik Protein, AA673177 Protein, Gctg Protein, Ggc Protein, Ggctl1 Protein, RGD1304876 Protein, RGD1562590 Protein, C7orf24 Protein, CRF21 Protein, GCTG Protein, GGC Protein, gamma-glutamylcyclotransferase b Protein, gamma-glutamylcyclotransferase Protein, gamma-glutamyl cyclotransferase Protein, ggctb Protein, GGCT Protein, ggct Protein, Ggct Protein
- Sub Type
- Fusionprotein
- Background
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Human Ypsilon-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.
Alternative Names: Gamma-Glutamylcyclotransferase, Cytochrome C-Releasing Factor 21, GGCT, C7orf24, CRF21 - Molecular Weight
- 23.17kDa
- UniProt
- O75223
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