DCXR Protein (AA 1-244) (His tag)
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- Target See all DCXR Proteins
- DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-244
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DCXR protein is labelled with His tag.
- Purpose
- Recombinant Human L-Xylulose Reductase/DCXR (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
- Characteristics
- Recombinant Human L-Xylulose Reductase/DCXR is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Cys244) of Human DCXR fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product DCXR Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 1 mM DTT, 30 % Glycerol, 1 mM DTT, pH 8.0.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
- Alternative Name
- L-Xylulose Reductase/DCXR (DCXR Products)
- Synonyms
- DCR Protein, HCR2 Protein, HCRII Protein, KIDCR Protein, P34H Protein, SDR20C1 Protein, XR Protein, dcxr Protein, DCXR Protein, DER Protein, 0610038K04Rik Protein, 1810027P18Rik Protein, glb Protein, wu:fa12f09 Protein, zgc:111977 Protein, GLB Protein, dicarbonyl and L-xylulose reductase Protein, dicarbonyl/L-xylulose reductase Protein, dicarbonyl L-xylulose reductase Protein, L-xylulose reductase Protein, L-xylulose reductase, putative Protein, dicarbonyl/L-xylulose reductase L homeolog Protein, DCXR Protein, dcxr Protein, Dcxr Protein, CNL05930 Protein, NCU09041 Protein, AOR_1_494194 Protein, VDBG_02657 Protein, CGB_D1070C Protein, dcxr.L Protein
- Sub Type
- Fusionprotein
- Background
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L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into Xylitol. L-Xylulose Reductase catalyzes the NADPH-dependent reduction of several Pentoses, Tetroses, Trioses, alpha-Dicarbonyl compounds and L-Xylulose. L-Xylulose Reductase participates in the Uronate Cycle of Glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing Xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Alternative Names: L-Xylulose Reductase, XR, Carbonyl Reductase II, Dicarbonyl/L-Xylulose Reductase, Kidney Dicarbonyl Reductase, kiDCR, Sperm Surface Protein P34H, DCXR - Molecular Weight
- 28.1 kDa
- UniProt
- Q7Z4W1
- Pathways
- Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process
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