NDRG1 Protein (AA 1-394) (His tag)
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- Target See all NDRG1 Proteins
- NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-394
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NDRG1 protein is labelled with His tag.
- Purpose
- Recombinant Human N-myc Downstream Regulated Gene 1/NDRG1/DRG-1CAP43 (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI SGWTQALPDM VVSHLFGKEE MQSNVEVVHT YRQHIVNDMN PGNLHLFINA YNSRRDLEIE RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLDGT RSRSHTSEGT RSRSHTSEGT RSRSHTSEGA HLDITPNSGA AGNSAGPKSM EVSC
- Characteristics
- Recombinant Human Protein NDRG1/NDRG1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Cys394) of Human NDRG1 fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product NDRG1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
- Alternative Name
- NDRG1 (NDRG1 Products)
- Synonyms
- CAP43 Protein, CMT4D Protein, DRG-1 Protein, DRG1 Protein, GC4 Protein, HMSNL Protein, NDR1 Protein, NMSL Protein, PROXY1 Protein, RIT42 Protein, RTP Protein, TARG1 Protein, TDD5 Protein, Ndr1 Protein, Ndrl Protein, cap43 Protein, cmt4d Protein, drg1 Protein, gc4 Protein, hmsnl Protein, ndr1 Protein, ndrg1 Protein, nmsl Protein, proxy1 Protein, rit42 Protein, rtp Protein, targ1 Protein, tdd5 Protein, xndrg1 Protein, ndrg4 Protein, cb775 Protein, wu:fb60h02 Protein, zgc:63944 Protein, NDRG1 Protein, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN Protein, non race-specific disease resistance 1 Protein, ndrg1-a Protein, ndrg1-b Protein, xNDRG1-A Protein, ndrg1l Protein, zgc:73047 Protein, N-myc downstream regulated 1 Protein, N-myc downstream regulated gene 1 Protein, N-myc downstream regulated 1 S homeolog Protein, N-myc downstream regulated 1a Protein, Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Protein, N-myc downstream regulated 1 L homeolog Protein, N-myc downstream regulated 1b Protein, NDRG1 Protein, Ndrg1 Protein, ndrg1.S Protein, ndrg1 Protein, ndrg1a Protein, NDR1 Protein, ndrg1.L Protein, ndrg1b Protein
- Sub Type
- Fusionprotein
- Background
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Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the alpha/beta Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression, overexpression of NDRG1 is connected to malignant status of esophageal cancer.
Alternative Names: Protein NDRG1, Differentiation-Related Gene 1 Protein, DRG-1, N-myc Downstream-Regulated Gene 1 Protein, Nickel-Specific Induction Protein Cap43, Reducing Agents and Tunicamycin-Responsive Protein, RTP, Rit42, NDRG1, CAP43, DRG1, RTP - Molecular Weight
- 45 kDa
- UniProt
- Q92597
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