NOL3 Protein (AA 1-208) (His tag)

Catalog No. ABIN1097254

Product Details

Target: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Protein Type: Recombinant

Protein Characteristics: AA 1-208

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NOL3 protein is labelled with His tag.

Purpose: Recombinant Human Nucleolar Protein 3/NOL3 (His)

Sequence: MGNAQERPSE TIDRERKRLV ETLQADSGLL LDALLARGVL TGPEYEALDA LPDAERRVRR LLLLVQGKGE AACQELLRCA QRTAGAPDPA WDWQHVGPGY RDRSYDPPCP GHWTPEAPGS GTTCPGLPRA SDPDEAGGPE GSEAVQSGTP EEPEPELEAE ASKEAEPEPE PEPELEPEAE AEPEPELEPE PDPEPEPDFE ERDESEDS

Characteristics:

Recombinant Human Nucleolar Protein 3/NOL3 (His)

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 25 mM TrisHCl, 1 mM DTT, 1 mM EDTA, 2 mM ß-ME, 20 % Glycerol, pH 7.5.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Alternative Name: Nucleolar Protein 3/NOL3 (NOL3 Products)

Synonyms: ARC Protein, FCM Protein, MYP Protein, NOP Protein, NOP30 Protein, B430311C09Rik Protein, MYC Protein, Nop30 Protein, Arc Protein, nucleolar protein 3 Protein, nucleolar protein 3 (apoptosis repressor with CARD domain) Protein, NOL3 Protein, Nol3 Protein

Background: Recombinant Human Nucleolar Protein 3/NOL3 (HIS-tagged) is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser208) of Human NOL3.
Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.It has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53.

Molecular Weight: 22.63 kDa

UniProt: O60936