Peroxiredoxin 6 Protein (PRDX6) (AA 2-224) (His tag)

Catalog No. ABIN1097323

Product Details

Target: Peroxiredoxin 6 (PRDX6)

Protein Type: Recombinant

Protein Characteristics: AA 2-224

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Peroxiredoxin 6 protein is labelled with His tag.

Purpose: Recombinant Human Peroxiredoxin-6/PRDX6 (N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MPGGLLLGDV APNFEANTTV GRIRFHDFLG DSWGILFSHP RDFTPVCTTE LGRAAKLAPE FAKRNVKLIA LSIDSVEDHL AWSKDINAYN CEEPTEKLPF PIIDDRNREL AILLGMLDPA EKDEKGMPVT ARVVFVFGPD KKLKLSILYP ATTGRNFDEI LRVVISLQLT AEKRVATPVD WKDGDSVMVL PTIPEEEAKK LFPKGVFTKE LPSGKKYLRY TPQP

Characteristics: Recombinant Human Peroxiredoxin-6/PRDX6 produced by our E. coli expression system. The target protein is expressed with sequence (Pro2-Pro224) of Human PRDX6 fused with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: Peroxiredoxin 6 (PRDX6)

Alternative Name: PRDX6 (PRDX6 Products)

Synonyms: 1-Cys Protein, AOP2 Protein, NSGPx Protein, PRX Protein, aiPLA2 Protein, p29 Protein, 1-cysPrx Protein, 9430088D19Rik Protein, AA690119 Protein, Aop2 Protein, Aop2-rs3 Protein, Brp-12 Protein, CC26 Protein, CP-3 Protein, GPx Protein, Ltw-4 Protein, Ltw4 Protein, Lvtw-4 Protein, NSGP Protein, ORF06 Protein, Prdx5 Protein, Prdx6-rs3 Protein, mKIAA0106 Protein, zgc:73360 Protein, aop2 Protein, prx-6 Protein, prx6 Protein, prdx6 Protein, PHGPX Protein, peroxiredoxin 6 Protein, peroxiredoxin 6 S homeolog Protein, peroxiredoxin 6 L homeolog Protein, PRDX6 Protein, Prdx6 Protein, prdx6 Protein, prdx6.S Protein, prdx6.L Protein

Sub Type: Fusionprotein

Background: Peroxiredoxin 6 belongs to the thiol-specific antioxidant protein family, which is a bifunctional enzyme with two distinct active sites. Peroxiredoxin 6 is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. Peroxiredoxin 6 may regulates phospholipid turnover and protectes against oxidative injury. Peroxiredoxin 6 eases the oxidative stress and TGF-beta-induced abnormalities of human trabecular meshwork cells, it is necessary for blood vessel integrity in injured skin.
Alternative Names: Peroxiredoxin-6, 1-Cys Peroxiredoxin, 1-Cys PRX, 24 kDa Protein, Acidic Calcium-Independent Phospholipase A2, aiPLA2, Antioxidant Protein 2, Liver 2D PAGE Spot 40, Non-Selenium Glutathione Peroxidase, NSGPx, Red Blood Cells Page Spot 12, PRDX6, AOP2, KIAA

Molecular Weight: 27.2 kDa

UniProt: P30041