ACPP Protein (AA 33-386) (His tag)

Catalog No. ABIN1097412

Product Details

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Protein Type: Recombinant

Protein Characteristics: AA 33-386

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This ACPP protein is labelled with His tag.

Purpose: Recombinant Human Prostatic Acid Phosphatase/ACPP (C-6His)

Sequence: KELKFVTLVF RHGDRSPIDT FPTDPIKESS WPQGFGQLTQ LGMEQHYELG EYIRKRYRKF LNESYKHEQV YIRSTDVDRT LMSAMTNLAA LFPPEGVSIW NPILLWQPIP VHTVPLSEDQ LLYLPFRNCP RFQELESETL KSEEFQKRLH PYKDFIATLG KLSGLHGQDL FGIWSKVYDP LYCESVHNFT LPSWATEDTM TKLRELSELS LLSLYGIHKQ KEKSRLQGGV LVNEILNHMK RATQIPSYKK LIMYSAHDTT VSGLQMALDV YNGLLPPYAS CHLTELYFEK GEYFVEMHYR NETQHEPYPL MLPGCSPSCP LERFAELVGP VIPQDWSTEC MTTNSHQGTE DSTDVDHHHH HH

Characteristics: Recombinant Human Prostatic Acid Phosphatase/ACPP produced by transfected human cells is a secreted protein with sequence (Lys33-Asp386) of Human ACPP fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Alternative Name: acpp (ACPP Products)

Synonyms: 5'-NT Protein, ACP-3 Protein, ACP3 Protein, PAP Protein, AMAP2 Protein, CENTB3 Protein, DDEF2 Protein, PAG3 Protein, Pap-alpha Protein, SHAG1 Protein, A030005E02Rik Protein, FRAP Protein, Lap Protein, Ppal Protein, Acpp11 Protein, RNACPP11 Protein, pap Protein, ACPP Protein, acp-3 Protein, acp3 Protein, acpt Protein, acid phosphatase, prostate Protein, ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 Protein, prostatic acid phosphatase Protein, prostatic acid phosphatase, putative Protein, acid phosphatase, prostate S homeolog Protein, ACPP Protein, ASAP2 Protein, Acpp Protein, CpipJ_CPIJ004002 Protein, Smp_016640 Protein, acpp.S Protein

Sub Type: Fusionprotein

Background: Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6, its activity can be inhibited by L(+)-tartrate.
Alternative Names: Prostatic Acid Phosphatase, PAP, 5'-Nucleotidase, 5'-NT, Ecto-5'-Nucleotidase, Thiamine Monophosphatase, TMPase, ACPP

Molecular Weight: 42.01 kDa

UniProt: P15309

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process