RPS19 Protein (AA 2-145)

Catalog No. ABIN1097469

Product Details

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Protein Type: Recombinant

Protein Characteristics: AA 2-145

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human 40S Ribosomal Protein S19/RPS19

Sequence: PGVTVKDVNQ QEFVRALAAF LKKSGKLKVP EWVDTVKLAK HKELAPYDEN WFYTRAASTA RHLYLRGGAG VGSMTKIYGG RQRNGVMPSH FSRGSKSVAR RVLQALEGLK MVEKDQDGGR KLTPQGQRDL DRIAGQVAAA NKKH

Characteristics: Recombinant Human 40S Ribosomal Protein S19/RPS19 is produced by our E. coli expression system. The target protein is expressed with sequence (Pro2-His145) of Human RPS19.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Alternative Name: rps19 (RPS19 Products)

Synonyms: DBA Protein, DBA1 Protein, S19 Protein, Dsk3 Protein, 30S ribosomal protein S19 Protein, 40S ribosomal protein S19 Protein, ribosomal protein S19 Protein, rps19 Protein, rps-19 Protein, RPS19 Protein, Rps19 Protein

Background: 40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1), which is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.
Alternative Names: 40S Ribosomal Protein S19, RPS19

Molecular Weight: 16.1 kDa

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly