SEMG1 Protein (AA 24-402) (His tag)
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- Target See all SEMG1 Proteins
- SEMG1 (Semenogelin I (SEMG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-402
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SEMG1 protein is labelled with His tag.
- Purpose
- Recombinant Human Semenogelin-1/SEMG1 (C-6His)
- Sequence
- QKGGSKGRLP SEFSQFPHGQ KGQHYSGQKG KQQTESKGSF SIQYTYHVDA NDHDQSRKSQ QYDLNALHKT TKSQRHLGGS QQLLHNKQEG RDHDKSKGHF HRVVIHHKGG KAHRGTQNPS QDQGNSPSGK GISSQYSNTE ERLWVHGLSK EQTSVSGAQK GRKQGGSQSS YVLQTEELVA NKQQRETKNS HQNKGHYQNV VEVREEHSSK VQTSLCPAHQ DKLQHGSKDI FSTQDELLVY NKNQHQTKNL NQDQQHGRKA NKISYQSSST EERRLHYGEN GVQKDVSQRS IYSQTEKLVA GKSQIQAPNP KQEPWHGENA KGESGQSTNR EQDLLSHEQK GRHQHGSHGG LDIVIIEQED DSDRHLAQHL NNDQNPLFTV DHHHHHH
- Characteristics
- Recombinant Human Semenogelin-1/SEMG1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln24-Thr402) of Human SEMG1 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SEMG1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Hac-NaAc, 150 mM NaCl, pH 4.5.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- SEMG1 (Semenogelin I (SEMG1))
- Alternative Name
- semg1 (SEMG1 Products)
- Synonyms
- SEMG1 Protein, SEMG1a Protein, CT103 Protein, SEMG Protein, SGI Protein, dJ172H20.2 Protein, RATSVPIIA Protein, SVPIIA Protein, SVS2P Protein, Svp1 Protein, Svs2 Protein, Svs2p2 Protein, BB115391 Protein, Semg1 Protein, SvsII Protein, semenogelin II Protein, semenogelin I Protein, semenogelin-2 Protein, seminal vesicle secretory protein 2 Protein, SEMG2 Protein, SEMG1 Protein, LOC100408385 Protein, Semg1 Protein, Svs2 Protein
- Sub Type
- Fusionprotein
- Background
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Semenogelin-1 (SEMG1) is the predominant protein in semen, it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alpha-inhibin-92 and alpha-inhibin-31 are produced, they inhibit the secretion of pituitary follicle-stimulating hormone. At the same time, it breaks down the gel matrix, allowing the spermatozoa to move more freely.
Alternative Names: Semenogelin-1, Semenogelin I, SGI, SEMG1, SEMG, Alpha-Inhibin-92, Alpha-Inhibin-31, Seminal Basic Protein - Molecular Weight
- 43.8 kDa
- UniProt
- P04279
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