LRP12 Protein (AA 28-488) (His tag)

Catalog No. ABIN1097586

Product Details

Target: LRP12 (Low Density Lipoprotein Receptor-Related Protein 12 (LRP12))

Protein Type: Recombinant

Protein Characteristics: AA 28-488

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This LRP12 protein is labelled with His tag.

Purpose: Recombinant Human Low-Density Lipoprotein Receptor Related Protein 12/LRP12 (C-6His)

Sequence: NGALAEHSEN VHISGVSTAC GETPEQIRAP SGIITSPGWP SEYPAKINCS WFIRANPGEI ITISFQDFDI QGSRRCNLDW LTIETYKNIE SYRACGSTIP PPYISSQDHI WIRFHSDDNI SRKGFRLAYF SGKSEEPNCA CDQFRCGNGK CIPEAWKCNN MDECGDSSDE EICAKEANPP TAAAFQPCAY NQFQCLSRFT KVYTCLPESL KCDGNIDCLD LGDEIDCDVP TCGQWLKYFY GTFNSPNYPD FYPPGSNCTW LIDTGDHRKV ILRFTDFKLD GTGYGDYVKI YDGLEENPHK LLRVLTAFDS HAPLTVVSSS GQIRVHFCAD KVNAARGFNA TYQVDGFCLP WEIPCGGNWG CYTEQQRCDG YWHCPNGRDE TNCTMCQKEE FPCSRNGVCY PRSDRCNYQN HCPNGSDEKN CFFCQPGNFH CKNNRCVFES WVCDSQDDCG DGSDEENCPV IVDHHHHHH

Characteristics:

Recombinant Human Low-Density Lipoprotein Receptor Related Protein 12/LRP12 (C-6His)

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: LRP12 (Low Density Lipoprotein Receptor-Related Protein 12 (LRP12))

Alternative Name: Low-Density Lipoprotein Receptor Related Protein 12 (LRP12 Products)

Synonyms: DKFZp459F2124 Protein, ST7 Protein, AI848829 Protein, C820005L12Rik Protein, LRP-12 Protein, LDL receptor related protein 12 Protein, low density lipoprotein-related protein 12 Protein, LRP12 Protein, lrp12 Protein, Lrp12 Protein

Background: Recombinant Human Low-Density Lipoprotein Receptor-Related Protein 12/LRP12 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu33-Arg492) of Human ST7 fused with a polyhistidine tag at the C-terminus.
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.

Molecular Weight: 52.48 kDa

UniProt: Q9Y561