Thymopoietin Protein (TMPO) (AA 2-187) (His tag)

Catalog No. ABIN1097643

Product Details

Target: Thymopoietin (TMPO)

Protein Type: Recombinant

Protein Characteristics: AA 2-187

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Thymopoietin protein is labelled with His tag.

Purpose: Recombinant Human Thymopoietin/TMPO/LAP2 (C-6His)

Sequence: MPEFLEDPSV LTKDKLKSEL VANNVTLPAG EQRKDVYVQL YLQHLTARNR PPLPAGTNSK GPPDFSSDEE REPTPVLGSG AAAAGRSRAA VGRKATKKTD KPRQEDKDDL DVTELTNEDL LDQLVKYGVN PGPIVGTTRK LYEKKLLKLR EQGTESRSST PLPTISSSAE NTRQNGSNDS DRYSDNELEH HHHHH

Characteristics: Recombinant Human Thymopoietin is produced by our E. coli expression system. The target protein is expressed with sequence (Pro2-Glu187) of Human Thymopoietin.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Thymopoietin (TMPO)

Alternative Name: thymopoietin (TMPO Products)

Synonyms: LAP2 Protein, CMD1T Protein, LEMD4 Protein, PRO0868 Protein, TP Protein, lap2 Protein, LAP2beta Protein, 5630400D24Rik Protein, AI195756 Protein, AI606875 Protein, AW214352 Protein, AW547477 Protein, tmpo Protein, wu:fc26f12 Protein, wu:fd21f02 Protein, wu:fi29h05 Protein, thymopoietin Protein, thymopoietin S homeolog Protein, thymopoietin a Protein, TMPO Protein, Tmpo Protein, tmpo.S Protein, tmpoa Protein

Background: Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus.
Alternative Names: Lamina-Associated Polypeptide 2 Isoforms Beta/Gamma, Thymopoietin Isoforms Beta/Gamma, TP Beta/Gamma, Thymopoietin-Related Peptide Isoforms Beta/Gamma, TPRP Isoforms Beta/Gamma, Thymopoietin, TP, Splenin, Thymopentin, TP5, TMPO, LAP2

Molecular Weight: 21.6 kDa

UniProt: P42167