TREM1 Protein (AA 21-201) (His tag)

Catalog No. ABIN1097700

Product Details

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Protein Type: Recombinant

Protein Characteristics: AA 21-201

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This TREM1 protein is labelled with His tag.

Purpose: Recombinant Human TREM-1/CD354 (C-6His)

Sequence: ATKLTEEKYE LKEGQTLDVK CDYTLEKFAS SQKAWQIIRD GEMPKTLACT ERPSKNSHPV QVGRIILEDY HDHGLLRVRM VNLQVEDSGL YQCVIYQPPK EPHMLFDRIR LVVTKGFSGT PGSNENSTQN VYKIPPTTTK ALCPLYTSPR TVTQAPPKST ADVSTPDSEI NLTNVTDIIR VDHHHHHH

Characteristics: Recombinant Human Triggering Receptor Expressed on Myeloid Cells 1/TREM-1 produced by transfected human cells is a secreted protein with sequence (Ala21-Val201) of Human TREM1 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Alternative Name: trem-1 (TREM1 Products)

Synonyms: TREM1 Protein, CD354 Protein, TREM-1 Protein, triggering receptor expressed on myeloid cells 1 Protein, TREM1 Protein, Trem1 Protein, LOC100349504 Protein

Sub Type: Fusionprotein

Background: Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain. TREM-1 associates with the adapter protein, DAP12, to deliver an activating signal. TREM-1 is expressed on blood neutrophils and monocytes, and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. Human TREM-1 shares 42% sequence homology with mouse TREM-1.
Alternative Names: Triggering Receptor Expressed on Myeloid Cells 1, TREM-1, Triggering Receptor Expressed on Monocytes 1, CD354, TREM1

Molecular Weight: 21.3 kDa

UniProt: Q9NP99