CARD18 Protein (His tag)
-
- Target See all CARD18 Proteins
- CARD18 (Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) (CARD18))
- Protein Type
- Recombinant
- Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CARD18 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CARD18 Protein
-
-
- Comment
-
Synonyms: Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, UNQ5804
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT,10% glycerol, 0.1 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- CARD18 (Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) (CARD18))
- Alternative Name
- CARD18 (CARD18 Products)
- Synonyms
- ICEBERG Protein, UNQ5804 Protein, pseudo-ICE Protein, caspase recruitment domain family member 18 Protein, CARD18 Protein
- Background
- Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 12.3 kDa (110aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_067546
-