GNAI3 Protein (His tag)
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- Target See all GNAI3 Proteins
- GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GNAI3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product GNAI3 Protein
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- Comment
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Synonyms: Guanine nucleotide-binding protein G(k) subunit alpha, 87U6
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 100 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))
- Alternative Name
- GNAI3 (GNAI3 Products)
- Synonyms
- AI158965 Protein, AW537698 Protein, Galphai3 Protein, Gnai-3 Protein, 87U6 Protein, ARCND1 Protein, GIP3A Protein, G protein subunit alpha i3 Protein, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 Protein, guanine nucleotide binding protein (G protein), alpha inhibiting 3 Protein, G protein subunit alpha i3 S homeolog Protein, GNAI3 Protein, gnai3 Protein, Gnai3 Protein, gnai3.S Protein
- Background
- GNAI3 belongs to the G-alpha family and G (i/o/t/z) subfamily. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. This protein plays a role in cell division. GNAI3 has been shown to interact with RGS14, RIC8A, RGS18, S1PR1, RGS12, RGS16, RGS19, RGS10 and RGS5. Recombinant human GNAI3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 43.0kDa (377aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_006487
- Pathways
- cAMP Metabolic Process, G-protein mediated Events
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