METAP1 Protein (His tag)
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- Target See all METAP1 Proteins
- METAP1 (Methionyl Aminopeptidase 1 (METAP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This METAP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product METAP1 Protein
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- Comment
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Synonyms: methionyl aminopeptidase 1, MAP1A, MetAP1A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 3mM DTT, 40% glycerol, 200 mM NaCl, 0.1 MM PMSF
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- METAP1 (Methionyl Aminopeptidase 1 (METAP1))
- Alternative Name
- METAP1 (METAP1 Products)
- Synonyms
- MGC64362 Protein, METAP1 Protein, metap1 Protein, DKFZp468B1413 Protein, LOC100228334 Protein, DDBDRAFT_0205763 Protein, DDBDRAFT_0235405 Protein, DDB_0205763 Protein, DDB_0235405 Protein, MAP1A Protein, MetAP1A Protein, 1700029C17Rik Protein, AW047992 Protein, mKIAA0094 Protein, Metap1 Protein, im:7047238 Protein, wu:fc84e12 Protein, zgc:110093 Protein, methionyl aminopeptidase 1 S homeolog Protein, methionyl aminopeptidase 1 Protein, methionine aminopeptidase 1 Protein, methionyl aminopeptidase 1 L homeolog Protein, metap1.S Protein, METAP1 Protein, metap1 Protein, Metap1 Protein, metap1.L Protein
- Background
- METAP1 (Methionine aminopeptidase 1) belongs to the peptidase M24A family. This protein removes the amino-terminal methionine from nascent proteins. It required for normal progression through the cell cycle. The active site of MetAP-1 contains two adjacent divalent metal ions connected by a water molecule or hydroxide ion. Recombinant human METAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 45.7kDa (409aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_055958
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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