CHMP6 Protein (His tag)
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- Target See all CHMP6 Proteins
- CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CHMP6 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CHMP6 Protein
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- Comment
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Synonyms: charged multivesicular body protein 6, VPS20
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 10% glycerol, 100 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
- Alternative Name
- CHMP6 (CHMP6 Products)
- Synonyms
- chmp6 Protein, vps20 Protein, 2400004G01Rik Protein, VPS20 Protein, RGD1565325 Protein, chmp6l Protein, flj11749l Protein, wu:fb79d02 Protein, zgc:110067 Protein, charged multivesicular body protein 6 Protein, charged multivesicular body protein 6 L homeolog Protein, charged multivesicular body protein 6 S homeolog Protein, charged multivesicular body protein 6b Protein, LOC100280982 Protein, chmp6.L Protein, chmp6.S Protein, CHMP6 Protein, chmp6 Protein, Tsp_08316 Protein, Chmp6 Protein, chmp6b Protein
- Background
- CHMP6, as known as charged multivesicular body protein 6, belongs to the SNF7 family. This Protein is core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Recombinant human CHMP6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 26.1kDa (225aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_078867
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