NEIL2 Protein (His tag)
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- Target See all NEIL2 Proteins
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NEIL2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product NEIL2 Protein
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Endonuclease 8-like 2 (NEIL2) (AA 1-332) protein (His tag)
NEIL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Endonuclease 8-like 2 (NEIL2) (AA 1-332) protein (GST tag)NEIL2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Endonuclease 8-like 2 (NEIL2) (AA 2-332) protein (His tag)Crystallography grade NEIL2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Endonuclease 8-like 2 (NEIL2) (AA 2-329) protein (His tag)Crystallography grade NEIL2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Endonuclease 8-like 2 (NEIL2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NEIL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Endonuclease 8-like 2 (NEIL2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NEIL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: Endonuclease 8-like 2, NEH2, NEI2, Nei-like protein 2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT, 10% glycerol, 0.1 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- Alternative Name
- NEIL2 (NEIL2 Products)
- Synonyms
- NEH2 Protein, NEI2 Protein, Gm1212 Protein, nei like DNA glycosylase 2 Protein, nei like 2 (E. coli) Protein, NEIL2 Protein, Neil2 Protein
- Background
- Endonuclease 8-like 2, also known as NEIL2, belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. It has negligible or undetectable activity with 8-oxoguanine, thymine glycol, 2-hydroxyadenine, hypoxanthine, and xanthine. Recombinant human NEIL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 39.4 kDa (356aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_659480
- Pathways
- DNA Damage Repair
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