PQBP1 Protein (His tag)
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- Target See all PQBP1 Proteins
- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PQBP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PQBP1 Protein
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Polyglutamine Binding Protein 1 (PQBP1) (AA 1-265) protein (His tag)
PQBP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Polyglutamine Binding Protein 1 (PQBP1) (AA 1-265) protein (GST tag)PQBP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Polyglutamine Binding Protein 1 (PQBP1) (AA 184-265) protein (GST tag)PQBP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Polyglutamine Binding Protein 1 (PQBP1) (AA 91-200) protein (GST tag)PQBP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Polyglutamine Binding Protein 1 (PQBP1) (AA 2-265) protein (His tag)Crystallography grade PQBP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Polyglutamine Binding Protein 1 (PQBP1) (AA 2-263) protein (His tag)Crystallography grade PQBP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Polyglutamine Binding Protein 1 (PQBP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PQBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Polyglutamine Binding Protein 1 (PQBP1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)PQBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Polyglutamine Binding Protein 1 (PQBP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PQBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Polyglutamine Binding Protein 1 (PQBP1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PQBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: Polyglutamine binding protein 1, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
- Alternative Name
- PQBP1 (PQBP1 Products)
- Synonyms
- PQBP1 Protein, MRX55 Protein, MRXS3 Protein, MRXS8 Protein, NPW38 Protein, RENS1 Protein, SHS Protein, PQBP-1 Protein, Sfc2 Protein, npw38 Protein, polyglutamine binding protein 1 Protein, PQBP1 Protein, Pqbp1 Protein
- Background
- Polyglutamine binding protein 1, also known as PQBP1, is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. Recombinant human PQBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 33 kDa (289aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_005701
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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