MAGEA6 Protein (His tag)

Catalog No. ABIN1098292

Product Details

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MAGEA6 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Purity: > 90 % by SDS - PAGE

Application Details

Comment:

Synonyms: Melanoma-associated antigen 6, CT1.6, MAGE-3b, MAGE3B, MAGE6

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 1 MM DTT

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Alternative Name: MAGEA6 (MAGEA6 Products)

Synonyms: Mage-a6 Protein, CT1.6 Protein, MAGE-3b Protein, MAGE3B Protein, MAGE6 Protein, melanoma antigen, family A, 6 Protein, MAGE family member A6 Protein, Magea6 Protein, MAGEA6 Protein

Background: MAGEA6 is a member of the MAGEA family, which directs the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes (CTL). The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. Recombinant human MAGEA6 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 35.9 kDa (322aa), confirmed by MALDI-TOF

NCBI Accession: NP_005354