Cyclin A Protein (His tag)
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- Target See all Cyclin A (CCNA2) Proteins
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Cyclin A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CCNA2 Protein
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Cyclin A2 (CCNA2) (AA 1-432) protein (GST tag)
CCNA2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cyclin A2 (CCNA2) (AA 268-432) protein (His-IF2DI Tag)CCNA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Cyclin A2 (CCNA2) (AA 144-264) protein (His-IF2DI Tag)CCNA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Cyclin A2 (CCNA2) (AA 1-100) protein (GST tag)CCNA2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cyclin A2 (CCNA2) (AA 1-422) protein (Strep Tag)Crystallography grade CCNA2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Cyclin A2 (CCNA2) protein (Myc-DYKDDDDK Tag)CCNA2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: Cyclin A2, CCN1, CCNA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.15 M NaCl, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
- Alternative Name
- CCNA2 (CCNA2 Products)
- Synonyms
- CCN1 Protein, CCNA Protein, AA408589 Protein, Ccn-1 Protein, Ccn1 Protein, Ccna Protein, CycA2 Protein, Cyca Protein, cb671 Protein, chunp6924 Protein, wu:fi36f03 Protein, CYCA Protein, Cyclin-A2 Protein, ccna2 Protein, ccn1 Protein, ccna Protein, ccna1 Protein, Cyclin-A Protein, cyclinA Protein, cyclin A2 Protein, cyclin A2 S homeolog Protein, cyclin A2 L homeolog Protein, CCNA2 Protein, Ccna2 Protein, ccna2 Protein, ccna2.S Protein, ccna2.L Protein
- Background
- CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Recombinant human CCNA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 51.1 kDa (456aa)
- NCBI Accession
- NP_001228
- Pathways
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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