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MYL12B Protein (His tag)

MYL12B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098301
  • Target See all MYL12B Proteins
    MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MYL12B protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product MYL12B Protein
  • Comment

    Synonyms: Myosin, light chain 12B regulatory, MLC-B, MRLC2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 40% glycerol, 2 mM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))
    Alternative Name
    MYL12B (MYL12B Products)
    Synonyms
    Mrlc2 Protein, Mrlcb Protein, Mylc2b Protein, MLC-B Protein, MRLC2 Protein, 1500001M02Rik Protein, C77744 Protein, RLC-B Protein, MYL12B Protein, mlc-b Protein, mrlc2 Protein, mrlcb Protein, myl12b Protein, myosin light chain 12B Protein, myosin, light chain 12B, regulatory Protein, Myosin regulatory light chain 2 Protein, myosin regulatory light chain 2 Protein, myosin regulatory light chain 12B Protein, myosin light chain 12B L homeolog Protein, Myl12b Protein, MYL12B Protein, mlc-2 Protein, MLC-2 Protein, LOC102175348 Protein, LOC101105123 Protein, LOC100062440 Protein, myl12b.L Protein
    Background
    Myosin, light chain 12B, regulatory, also known as MYL12B, is a hexameric ATPase cellular motor protein. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. MYL12B regulates contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases Actin-activated myosin ATPase activity, thereby regulating contractile activity. Recombinant human MYL12B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    22.3 kDa (196aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_001138417
    Pathways
    Feeding Behaviour
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