Destrin Protein (His tag)
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- Target See all Destrin (DSTN) Proteins
- Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Destrin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DSTN Protein
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Destrin (Actin Depolymerizing Factor) (DSTN) (AA 1-165) protein (His tag)
DSTN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Destrin (Actin Depolymerizing Factor) (DSTN) (AA 1-165) protein (GST tag)DSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Destrin (Actin Depolymerizing Factor) (DSTN) (AA 56-164) protein (GST tag)DSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Destrin (Actin Depolymerizing Factor) (DSTN) (AA 2-165) protein (His tag)Crystallography grade DSTN Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Destrin (Actin Depolymerizing Factor) (DSTN) (AA 2-165) protein (His tag)Crystallography grade DSTN Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Destrin (Actin Depolymerizing Factor) (DSTN) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DSTN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: Destrin (actin depolymerizing factor), ACTDP, ADF, bA462D18.2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))
- Alternative Name
- DSTN (DSTN Products)
- Synonyms
- ACTDP Protein, ADF Protein, bA462D18.2 Protein, DSTN Protein, LOC100190417 Protein, adf Protein, actdp Protein, ba462d18.2 Protein, 2610043P17Rik Protein, AU042046 Protein, Dsn Protein, corn1 Protein, sid23p Protein, destrin Protein, destrin, actin depolymerizing factor Protein, destrin Protein, destrin, actin depolymerizing factor S homeolog Protein, DSTN Protein, dstn Protein, Dstn Protein, dstn.S Protein
- Background
- Destrin (actin depolymerizing factor), also known as DSTN, is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. DSTN is a small phosphoinositide-sensitive actin-binding protein capable of depolymerizing actin-filaments in vitro. It is found in various epithelial and endothelial cells but is practically absent from adult mouse heart and skeletal muscle cells. DSTN shares 71% sequence homology with Cofilin, however the two proteins differ in their interaction with Actin. Recombinant human DSTN protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 19.5 kDa (173aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_006861
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