TIRAP Protein (His tag)
-
- Target See all TIRAP Proteins
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TIRAP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TIRAP Protein
-
-
- Comment
-
Synonyms: toll-interleukin1 receptor (TIR) domain containing adaptor protein, BACTS1, Mal, wyatt
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 20% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- Alternative Name
- TIRAP (TIRAP Products)
- Synonyms
- mal Protein, wyatt Protein, BACTS1 Protein, Mal Protein, MyD88-2 Protein, AA407980 Protein, C130027E04Rik Protein, Tlr4ap Protein, Wyatt Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein Protein, TIR domain containing adaptor protein Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog Protein, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein Protein, tirap Protein, TIRAP Protein, tirap.L Protein, Tirap Protein
- Background
- TIRAP (toll-interleukin1 receptor (TIR) domain containing adaptor protein) contains 1 TIR domain. This protein is an adapter molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Adapter protein, TIRAP, is involved in TLR2 and TLR4 signaling pathways in the innate immune response. Recombinant human TIRAP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 26.3 kDa (244aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_001034750
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
-