ULBP1 Protein (His tag)
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- Target See all ULBP1 Proteins
- ULBP1 (UL16 Binding Protein 1 (ULBP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ULBP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ULBP1 Protein
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UL16 Binding Protein 1 (ULBP1) protein (His-Avi Tag)
ULBP1 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
UL16 Binding Protein 1 (ULBP1) protein (His-Avi Tag,Biotin)ULBP1 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
UL16 Binding Protein 1 (ULBP1) (AA 26-216) protein (His tag)ULBP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
UL16 Binding Protein 1 (ULBP1) (AA 1-244) protein (GST tag)ULBP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
UL16 Binding Protein 1 (ULBP1) (AA 26-216) protein (His tag)Crystallography grade ULBP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- Comment
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Synonyms: NKG2D ligand 1, UL16 binding protein 1, RAET1I, N2DL-1, N2DL1, NKG2D ligand 1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 30% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- ULBP1 (UL16 Binding Protein 1 (ULBP1))
- Alternative Name
- ULBP1 (ULBP1 Products)
- Synonyms
- RAET1I Protein, A430108B07Rik Protein, MULT1 Protein, ULBP1 Protein, UL16 binding protein 1 Protein, UL16 binding protein 21 Protein, NKG2D ligand 1 Protein, ULBP1 Protein, ULBP21 Protein, Ulbp1 Protein, LOC100683099 Protein
- Background
- ULBP1 is ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. In CMV infected cells, ULBP1 interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. Recombinant human ULBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 25 kDa (216aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_079494
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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