SIX Homeobox 6 Protein (SIX6) (His tag)
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- Target See all SIX Homeobox 6 (SIX6) Proteins
- SIX Homeobox 6 (SIX6)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SIX Homeobox 6 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SIX6 Protein
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- Comment
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Synonyms: SIX homeobox 6, MCOPCT2, Six9
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 40% glycerol, 5 MM DTT, 2 mM EDTA
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- SIX Homeobox 6 (SIX6)
- Alternative Name
- SIX6 (SIX6 Products)
- Synonyms
- MCOPCT2 Protein, OPTX2 Protein, Six9 Protein, Optx2 Protein, Six6 Protein, MGC63871 Protein, zgc:63871 Protein, Six6.1 Protein, Six6.2 Protein, XOptx2 Protein, optx2 Protein, xSix6 Protein, si:dkey-225h23.3 Protein, zgc:110344 Protein, SIX homeobox 6 Protein, sine oculis-related homeobox 6 Protein, SIX homeobox 6a Protein, SIX homeobox 6 L homeolog Protein, SIX homeobox 6b Protein, SIX6 Protein, Six6 Protein, six6a Protein, six6.L Protein, six6b Protein
- Background
- SIX6, also as known as OPTX2 and SIX9, belongs to the SIX/Sine oculis homeobox family contains 1 homeobox DNA-binding domain. The SIX homeobox protein is crucial in embryonic development by providing necessary instructions for the formation of the forebrain and eye development. This protein expressed in the developing and adult retina, hypothalamic and the pituitary regions. Defects in SIX6 are the cause of microphthalmia isolated with cataract type 2. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Recombinant human SIX6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 30.1kDa (269aa) confirmed by MALDI-TOF
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