XAGE1 Protein (His tag)

Catalog No. ABIN1098424

Product Details

Target: XAGE1 (XAGE1A) (X Antigen Family, Member 1A (XAGE1A))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This XAGE1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Purity: > 85 % by SDS - PAGE

Application Details

Comment:

Synonyms: G antigen family D member 2, CT12.1, CT12.1A, CTP9, GAGED2, XAGE1, XAGE1B, XAGE1C, XAGE1D, XAGE1E

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 20% glycerol, 2 mM DTT

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: XAGE1 (XAGE1A) (X Antigen Family, Member 1A (XAGE1A))

Alternative Name: XAGE1A (XAGE1A Products)

Background: G antigen family D member 2, also known as XAGE1A, is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT(cancer-testis) antigens. Recombinant human XAGE1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 11.5 kDa (104aa) confirmed by MALDI-TOF

NCBI Accession: NP_001091061