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Asialoglycoprotein Receptor 2 Protein (ASGR2) (His tag)

ASGR2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098437
  • Target See all Asialoglycoprotein Receptor 2 (ASGR2) Proteins
    Asialoglycoprotein Receptor 2 (ASGR2)
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Asialoglycoprotein Receptor 2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ASGR2 Protein
  • Comment

    Synonyms: Asialoglycoprotein receptor 2, ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol, 1 MM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    Asialoglycoprotein Receptor 2 (ASGR2)
    Alternative Name
    ASGR2 (ASGR2 Products)
    Synonyms
    ASGR2 Protein, asgr2 Protein, MGC137129 Protein, ASGP-R2 Protein, ASGPR2 Protein, CLEC4H2 Protein, HBXBP Protein, HL-2 Protein, Asgr Protein, Asgr-2 Protein, asialoglycoprotein receptor 2 Protein, C-type lectin domain family 10 member A Protein, ASGR2 Protein, clec10a Protein, Asgr2 Protein, LOC100347178 Protein
    Background
    ASGR2 is a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. It may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. ASGR2 is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human ASGR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    28.9 kDa (255aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_001172
    Pathways
    Thyroid Hormone Synthesis
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