CLNS1A Protein (His tag)
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- Target See all CLNS1A Proteins
- CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CLNS1A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CLNS1A Protein
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Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 1-237) protein (His tag)
CLNS1A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 1-237) protein (GST tag)CLNS1A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 2-237) protein (His tag)Crystallography grade CLNS1A Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 2-236) protein (His tag)Crystallography grade CLNS1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- Comment
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Synonyms: Methylosome subunit pICln, CLCI, CLNS1B, Icln
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))
- Alternative Name
- CLNS1A (CLNS1A Products)
- Synonyms
- CLCI Protein, CLNS1B Protein, ICln Protein, 2610036D06Rik Protein, 2610100O04Rik Protein, Clci Protein, Clcni Protein, ICLN Protein, Icln Protein, pICln Protein, clci Protein, clns1b Protein, icln Protein, pIcIn Protein, chloride nucleotide-sensitive channel 1A Protein, chloride channel, nucleotide-sensitive, 1A Protein, chloride channel, nucleotide-sensitive, 1A L homeolog Protein, CLNS1A Protein, Clns1a Protein, clns1a.L Protein, clns1a Protein
- Background
- CLNS1A, also as known as, Methylosome subunit pICln, belongs to the pICln (TC 1.A.47) family. CLNS1A protein has functions in multiple regulatory pathways. This protein interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. It is Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. And this protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Recombinant human CLNS1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 28.8kDa (261aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_001284
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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