SH3GLB1 Protein (His tag)
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- Target See all SH3GLB1 Proteins
- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SH3GLB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SH3GLB1 Protein
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- Comment
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Synonyms: Endophilin-B1, Bif-1, CGI-61, dJ612B15.2, PPP1R70
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
- Alternative Name
- SH3GLB1 (SH3GLB1 Products)
- Background
- SH3GLB1, also as known as endophilin-B1, belongs to the endophilin family. Endophilin B1 is a member of the B subgroup of the endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. This protein required for normal outer mitochondrial membrane dynamics. Also it required for coatomer-mediated retrograde transport in certain cells. SH3GLB1 has been shown to interact with SH3GLB2 and Bcl-2-associated X protein. This protein highly expressed in heart, skeletal muscle, kidney and placenta. Recombinant human SH3GLB1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 41.9kDa (373aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_057093
- Pathways
- Autophagy
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