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CD3 epsilon Protein (CD3E) (His tag)

CD3E Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098484
  • Target See all CD3 epsilon (CD3E) Proteins
    CD3 epsilon (CD3E)
    Protein Type
    Recombinant
    Origin
    • 25
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 23
    • 8
    • 5
    • 5
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CD3 epsilon protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product CD3E Protein
  • Comment

    Synonyms: T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 10% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    CD3 epsilon (CD3E)
    Alternative Name
    CD3E (CD3E Products)
    Synonyms
    cd3e Protein, CD3E Protein, t3e Protein, tcre Protein, AI504783 Protein, CD3 Protein, CD3epsilon Protein, T3e Protein, T3E Protein, TCRE Protein, CD3e molecule Protein, CD3 antigen, epsilon polypeptide Protein, cd3e Protein, CD3E Protein, Cd3e Protein
    Background
    CD3E is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. Recombinant human CD3E protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    14.1 kDa (127aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_000724
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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