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BCL2L10 Protein (His tag)

BCL2L10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098488
  • Target See all BCL2L10 Proteins
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This BCL2L10 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
  • Comment

    Synonyms: Bcl-2-like protein 10, BCL-B, Boo, Diva

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Alternative Name
    BCL2L10 (BCL2L10 Products)
    Synonyms
    BCL-B Protein, Boo Protein, Diva Protein, AA420380 Protein, AU023065 Protein, C85687 Protein, NR-13 Protein, mcl1l Protein, nr13 Protein, sb:cb78 Protein, BCL2 like 10 Protein, Bcl2-like 10 Protein, BCL2-like 10 (apoptosis facilitator) Protein, BCL2L10 Protein, Bcl2l10 Protein, bcl2l10 Protein
    Background
    BCL2L10 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L10 contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this protein has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. Recombinant human BCL2L10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    21.8 kDa (195aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_065129
    Pathways
    Positive Regulation of Endopeptidase Activity
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