BCL2L10 Protein (His tag)
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- Target See all BCL2L10 Proteins
- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BCL2L10 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
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- Comment
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Synonyms: Bcl-2-like protein 10, BCL-B, Boo, Diva
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
- Alternative Name
- BCL2L10 (BCL2L10 Products)
- Synonyms
- BCL-B Protein, Boo Protein, Diva Protein, AA420380 Protein, AU023065 Protein, C85687 Protein, NR-13 Protein, mcl1l Protein, nr13 Protein, sb:cb78 Protein, BCL2 like 10 Protein, Bcl2-like 10 Protein, BCL2-like 10 (apoptosis facilitator) Protein, BCL2L10 Protein, Bcl2l10 Protein, bcl2l10 Protein
- Background
- BCL2L10 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L10 contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this protein has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. Recombinant human BCL2L10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 21.8 kDa (195aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_065129
- Pathways
- Positive Regulation of Endopeptidase Activity
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