CD247 Protein (His tag)
-
- Target See all CD247 Proteins
- CD247 (CD247 Molecule (CD247))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CD247 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CD247 Protein
-
CD247 Molecule (CD247) (AA 62-164) protein (His tag)
CD247 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
CD247 Molecule (CD247) (AA 1-164) protein (GST tag)CD247 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
CD247 Molecule (CD247) (AA 52-164) protein (His tag)Crystallography grade CD247 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
CD247 Molecule (CD247) (AA 52-164) protein (His tag)Crystallography grade CD247 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
CD247 Molecule (CD247) (AA 22-164) protein (rho-1D4 tag)Crystallography grade CD247 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
CD247 Molecule (CD247) (AA 22-164) protein (rho-1D4 tag)Crystallography grade CD247 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
-
- Comment
-
Synonyms: T-cell surface glycoprotein CD3 zeta chain, CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- CD247 (CD247 Molecule (CD247))
- Alternative Name
- CD247 (CD247 Products)
- Synonyms
- CD3-ZETA Protein, CD3H Protein, CD3Q Protein, CD3Z Protein, T3Z Protein, TCRZ Protein, 4930549J05Rik Protein, A430104F18Rik Protein, AW552088 Protein, Cd3 Protein, Cd3-eta Protein, Cd3-zeta Protein, Cd3h Protein, Cd3z Protein, Cd3zeta Protein, T3z Protein, Tcrk Protein, Tcrz Protein, LOC100136514 Protein, LOC100136549 Protein, LOC100305023 Protein, CD247 Protein, TCRzeta Protein, CD247 molecule Protein, CD247 antigen Protein, CD3zeta-2 Protein, CD3zeta-1 Protein, Cd247 molecule Protein, CD247 Protein, Cd247 Protein, cd3z Protein, cd247 Protein
- Background
- T-cell surface glycoprotein CD3 zeta chain, also known as CD247, belongs to the CD3Z/FCER1G family. CD247 is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Recombinant human CD247 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 15.4kDa (136aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_932170
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
-
