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BPIFA1 Protein (His tag)

BPIFA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098511
  • Target See all BPIFA1 Proteins
    BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 1
    • 1
    Human
    Source
    • 6
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This BPIFA1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product BPIFA1 Protein
  • Comment

    Synonyms: BPI fold-containing family A, member 1, bA49G10.5, LPLUNC3, LUNX, NASG, PLUNC, SPURT

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by BCA assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))
    Alternative Name
    BPIFA1 (BPIFA1 Products)
    Synonyms
    LUNX Protein, NASG Protein, PLUNC Protein, SPLUNC1 Protein, SPURT Protein, bA49G10.5 Protein, Plunc Protein, BPI fold containing family A member 1 Protein, BPI fold containing family A, member 1 Protein, BPIFA1 Protein, Bpifa1 Protein
    Background
    BPIFA1, also known as PLUNC, belongs to the short subfamily of PLUNC family proteins and have homology only to the Nterminal domains of BPI. It is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. BPIFA1 binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of BPIFA1 occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of BPIFA1 in the upper respiratory tract. Recombinant human BPIFA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    27.1 kDa (260aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_057667
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