PIM1 Protein (His tag)
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- Target See all PIM1 Proteins
- PIM1 (Pim-1 Oncogene (PIM1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PIM1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PIM1 Protein
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Pim-1 Oncogene (PIM1) (AA 1-313) (Active) protein (His tag)
PIM1 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Pim-1 Oncogene (PIM1) (AA 1-313) (Active) protein (His-GST)PIM1 Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Pim-1 Oncogene (PIM1) (AA 38-290) protein (His tag)PIM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Pim-1 Oncogene (PIM1) (AA 1-313) protein (GST tag)PIM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pim-1 Oncogene (PIM1) (AA 1-100) protein (GST tag)PIM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pim-1 Oncogene (PIM1) (AA 1-404) protein (His tag)Crystallography grade PIM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Pim-1 Oncogene (PIM1) (AA 1-397) protein (His tag)Crystallography grade PIM1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Comment
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Synonyms: Non-specific serine/threonine protein kinase, PIM
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- PIM1 (Pim-1 Oncogene (PIM1))
- Alternative Name
- Pim1 (PIM1 Products)
- Synonyms
- PIM Protein, Pim-1 Protein, PIM1 Protein, pim Protein, pim-1 Protein, pim3 Protein, Pim-1 proto-oncogene, serine/threonine kinase Protein, proviral integration site 1 Protein, Pim-1 proto-oncogene, serine/threonine kinase L homeolog Protein, PIM1 Protein, Pim1 Protein, pim1 Protein, pim1.L Protein
- Background
- PIM1 belongs to the Ser/Thr protein kinase family, and PIM subfamily. This protein is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. Recombinant human Pim1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 31.4 kDa (274aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_002639
- Pathways
- Glycosaminoglycan Metabolic Process
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