GULP1 Protein (His tag)
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- Target See all GULP1 Proteins
- GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GULP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GULP1 Protein
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- Comment
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Synonyms: PTB domain-containing engulfment adapter protein 1, CED-6, CED6, GULP
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 50% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))
- Alternative Name
- GULP1 (GULP1 Products)
- Synonyms
- GULP1 Protein, CED-6 Protein, CED6 Protein, GULP Protein, 3110030A04Rik Protein, 5730529O06Rik Protein, Ced6 Protein, Gulp-2 Protein, gulp1 Protein, si:by35d8.1 Protein, si:ch211-198b21.4 Protein, si:xx-35d8.1 Protein, wu:fj61e02 Protein, GULP, engulfment adaptor PTB domain containing 1 Protein, CED-6 protein Protein, ced-6 protein Protein, GULP, engulfment adaptor PTB domain containing 1a Protein, GULP1 Protein, gulp1 Protein, Bm1_18525 Protein, ced-6 Protein, Gulp1 Protein, gulp1a Protein
- Background
- PTB domain-containing engulfment adapter protein 1, also known as GULP1, is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes. GULP1 also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GULP1 are associated with increases in cellular levels of GTP-bound ARF6. Recombinant human GULP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 36.9kDa (327aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_057399
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