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GULP1 Protein (His tag)

GULP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN1098569
  • Target See all GULP1 Proteins
    GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GULP1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product GULP1 Protein
  • Comment

    Synonyms: PTB domain-containing engulfment adapter protein 1, CED-6, CED6, GULP

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 50% glycerol, 2 mM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))
    Alternative Name
    GULP1 (GULP1 Products)
    Synonyms
    GULP1 Protein, CED-6 Protein, CED6 Protein, GULP Protein, 3110030A04Rik Protein, 5730529O06Rik Protein, Ced6 Protein, Gulp-2 Protein, gulp1 Protein, si:by35d8.1 Protein, si:ch211-198b21.4 Protein, si:xx-35d8.1 Protein, wu:fj61e02 Protein, GULP, engulfment adaptor PTB domain containing 1 Protein, CED-6 protein Protein, ced-6 protein Protein, GULP, engulfment adaptor PTB domain containing 1a Protein, GULP1 Protein, gulp1 Protein, Bm1_18525 Protein, ced-6 Protein, Gulp1 Protein, gulp1a Protein
    Background
    PTB domain-containing engulfment adapter protein 1, also known as GULP1, is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes. GULP1 also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GULP1 are associated with increases in cellular levels of GTP-bound ARF6. Recombinant human GULP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    36.9kDa (327aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_057399
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