BCL10 Protein (His tag)
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- Target See all BCL10 Proteins
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BCL10 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product BCL10 Protein
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B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) protein (GST tag)
BCL10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) protein (Strep Tag)Crystallography grade BCL10 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) protein (Strep Tag)Crystallography grade BCL10 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233), (full length) protein (His-SUMO Tag)BCL10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Comment
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Synonyms: B-cell lymphoma/leukemia 10, c-E10, CARMEN, CIPER, CLAP, mE10
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.05 M NaCl, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
- Alternative Name
- BCL10 (BCL10 Products)
- Synonyms
- CARMEN Protein, CIPER Protein, CLAP Protein, c-E10 Protein, mE10 Protein, BCL10 Protein, AI132454 Protein, BCL-10 Protein, C81403 Protein, ME10 Protein, cE10 Protein, bcl10 Protein, B-cell CLL/lymphoma 10 Protein, B-cell lymphoma/leukemia 10-like Protein, B cell leukemia/lymphoma 10 Protein, B-cell lymphoma/leukemia 10 Protein, BCL10 Protein, Bcl10 Protein, bcl10 Protein, LOC100223183 Protein
- Background
- BCL10, also known as B-cell lymphoma/leukemia 10, contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. It is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Recombinant human BCL10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 28.8 kDa (257aa) confirmed by MALDI-TOF (molecular weight on SDS-PAGE will appear higher)
- NCBI Accession
- NP_003912
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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