APIP Protein (His tag)
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- Target See all APIP Proteins
- APIP (APAF1 Interacting Protein (APIP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This APIP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product APIP Protein
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- Comment
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Synonyms: Probable methylthioribulose-1-phosphate dehydratase, APIP2, CGI-29, CGI29, dJ179L10.2, MMRP19
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- APIP (APAF1 Interacting Protein (APIP))
- Alternative Name
- APIP (APIP Products)
- Synonyms
- APIP2 Protein, CGI29 Protein, MMRP19 Protein, dJ179L10.2 Protein, hAPIP Protein, CGI-29 Protein, Mmrp19 Protein, RGD1564562 Protein, zgc:103619 Protein, APAF1 interacting protein Protein, APAF1 interacting protein S homeolog Protein, APIP Protein, Apip Protein, apip Protein, apip.S Protein
- Background
- APIP, also known as probable methylthioribulose-1-phosphate dehydratase, catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). It has an anti-apoptotic function and prevents muscle ischemic damage. This protein inhibits the cytochrome c-dependent and APAF1-mediated cell death. Recombinant human APIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 29.7 kDa (266aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_057041
- Pathways
- Methionine Biosynthetic Process
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