Kallikrein 7 Protein (KLK7) (His tag)
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- Target See all Kallikrein 7 (KLK7) Proteins
- Kallikrein 7 (KLK7)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Kallikrein 7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product KLK7 Protein
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- Comment
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Synonyms: kallikrein-7, hK7, PRSS6, SCCE
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Kallikrein 7 (KLK7)
- Alternative Name
- KLK7 (KLK7 Products)
- Synonyms
- Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein
- Background
- KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Recombinant human KLK7 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 27.1 kDa (249aa)
- NCBI Accession
- NP_005037
- Pathways
- Complement System
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