UMPS Protein (His tag)
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- Target See all UMPS Proteins
- UMPS (Uridine Monophosphate Synthetase (UMPS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UMPS protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product UMPS Protein
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Uridine Monophosphate Synthetase (UMPS) (AA 1-480) protein (GST tag)
UMPS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Uridine Monophosphate Synthetase (UMPS) (AA 381-479) protein (GST tag)UMPS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Uridine Monophosphate Synthetase (UMPS) (AA 2-480) protein (His tag)Crystallography grade UMPS Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Uridine Monophosphate Synthetase (UMPS) (Active) protein (Myc-DYKDDDDK Tag)UMPS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Uridine Monophosphate Synthetase (UMPS) (AA 1-480) protein (His tag)UMPS Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
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- Comment
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Synonyms: Uridine 5'-monophosphate synthase, OPRT
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- UMPS (Uridine Monophosphate Synthetase (UMPS))
- Alternative Name
- UMPS (UMPS Products)
- Synonyms
- zgc:55702 Protein, zgc:55723 Protein, UMPS Protein, OPRT Protein, 1700095D23Rik Protein, AA408257 Protein, AL033308 Protein, BB164745 Protein, Orotidine 5'-phosphate decarboxylase Protein, uridine monophosphate synthetase Protein, uridine monophosphate synthetase L homeolog Protein, uridine 5'-monophosphate synthase Protein, umps-1 Protein, umps Protein, umps.L Protein, UMPS Protein, LOC100556619 Protein, Umps Protein
- Background
- Uridine 5'-monophosphate synthase, also known as UMPS, is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. Unlike prokaryotes, UMPS in eukaryotes combines the orotate phosphoribosyltransferase and the orotidine-5’-monophosphate (OMP) decarboxylase activities into a single protein. The union of these two enzymes is thought to stabilize the catalytic centers due to the low molar concentration of the protein in mammalian cells. Defects in this gene are the cause of hereditary orotic aciduria. Recombinant human UMPS protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 54.3 kDa (500aa)
- NCBI Accession
- NP_000364
- Pathways
- Ribonucleoside Biosynthetic Process
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