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SPINT2 Protein (His tag)

SPINT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN1098709
  • Target See all SPINT2 Proteins
    SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    Human
    Source
    • 3
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SPINT2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purity
    > 85 % by SDS - PAGE
  • Comment

    Synonyms: Kunitz-type protease inhibitor 2, DIAR3, FLJ45571, HAI-2, HAI2, Kop, PB

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea 10% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))
    Alternative Name
    SPINT2 (SPINT2 Products)
    Synonyms
    HAI-2 Protein, Pb Protein, DIAR3 Protein, HAI2 Protein, Kop Protein, PB Protein, AL024025 Protein, C76321 Protein, serine peptidase inhibitor, Kunitz type, 2 Protein, serine peptidase inhibitor, Kunitz type 2 Protein, serine protease inhibitor, Kunitz type 2 Protein, Spint2 Protein, SPINT2 Protein
    Background
    SPINT2 is a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This protein is a putative tumor suppressor, and mutations in this protein result in congenital sodium diarrhea. Recombinant human SPINT2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    21.8 kDa (195aa)
    NCBI Accession
    NP_066925
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