IRGM Protein (His tag)
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- Target See all IRGM Proteins
- IRGM (Immunity-Related GTPase Family, M (IRGM))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IRGM protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product IRGM Protein
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Immunity-Related GTPase Family, M (IRGM) (AA 99-181) protein (GST tag)
IRGM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Immunity-Related GTPase Family, M (IRGM) (AA 1-181) protein (Strep Tag)Crystallography grade IRGM Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Immunity-Related GTPase Family, M (IRGM) (AA 1-409) protein (Strep Tag)Crystallography grade IRGM Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Comment
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Synonyms: Immunity-related GTPase family M protein, IFI1, IRGM1, LRG-47, LRG47, MGC149263, MGC149264
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- IRGM (Immunity-Related GTPase Family, M (IRGM))
- Alternative Name
- IRGM (IRGM Products)
- Synonyms
- Ifi1 Protein, Iigp3 Protein, Iipg3 Protein, Irgm Protein, LRG-47 Protein, IFI1 Protein, IRGM1 Protein, LRG47 Protein, immunity-related GTPase family M member 1 Protein, immunity-related GTPase M Protein, immunity related GTPase M Protein, immunity-related GTPase family M protein Protein, Irgm1 Protein, Irgm Protein, IRGM Protein, LOC481473 Protein
- Background
- Immunity-related GTPase family M protein, also known as IRGM, is required for clearance of acute protozoan and bacterial infections. This protein functions in innate immune response probably through regulation of autophagy. It may regulate proinflammatory cytokine production and prevent endotoxemia upon infection and may also play a role in macrophages adhesion and motility. Recombinant human IRGM protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 20.1 kDa (180aa)
- NCBI Accession
- NP_001139277
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