NKX3-1 Protein (His tag)
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- Target See all NKX3-1 Proteins
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NKX3-1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product NKX3-1 Protein
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- Comment
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Synonyms: Homeobox protein Nkx-3.1, BAPX2, NKX3, NKX3.1, NKX3A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
- Alternative Name
- NKX3-1 (NKX3-1 Products)
- Synonyms
- Xbagpipe Protein, Xbap Protein, bagpipe Protein, koza Protein, nkx3-1 Protein, nkx3.1 Protein, si:ch211-67o1.2 Protein, nkx3a Protein, MGC53041 Protein, MGC97890 Protein, Bax Protein, NKX3.1 Protein, NKX3A Protein, Nkx-3.1 Protein, BAPX2 Protein, NKX3 Protein, NK3 homeobox 1 L homeolog Protein, NK3 homeobox 1 Protein, NK-3 transcription factor, locus 1 (Drosophila) Protein, nkx3-1.L Protein, NKX3-1 Protein, nkx3-1 Protein, Nkx3-1 Protein
- Background
- NKX3-1 is a homeobox-containing transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of NKX3-1 is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this. Recombinant human NKX3-1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 28.7kDa (257aa)
- NCBI Accession
- NP_006158
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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