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XPA Protein (His tag)

XPA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN1098757
  • Target See all XPA Proteins
    XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This XPA protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product XPA Protein
  • Comment

    Synonyms: DNA repair protein complementing XP-A cells, XP1, XPAC

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
    Alternative Name
    XPA (XPA Products)
    Synonyms
    CG6358 Protein, DhR14 Protein, DhXPA Protein, DmXPA Protein, Dmel\\CG6358 Protein, Dxpa Protein, EG:EG0007.8 Protein, XPAC Protein, XPA_DROME Protein, Xpa Protein, dmXPA Protein, dxpa Protein, XP1 Protein, AI573865 Protein, Xpac Protein, xpac Protein, xxpa Protein, Xeroderma pigmentosum group A-like Protein, XPA, DNA damage recognition and repair factor Protein, xeroderma pigmentosum, complementation group A Protein, xeroderma pigmentosum, complementation group A L homeolog Protein, Xpac Protein, XPA Protein, Xpa Protein, xpa.L Protein
    Background
    XPA, also known as DNA repair protein complementing XP-A cells, belong to the XPA family. This protein is involved in DNA excision repair. It Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A), which is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Recombinant human XPA protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    33.8 kDa (296aa)
    NCBI Accession
    NP_000371
    Pathways
    DNA Damage Repair
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