IL18BP Protein (His tag)
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- Target See all IL18BP Proteins
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL18BP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product IL18BP Protein
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- Comment
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Synonyms: Interleukin-18-binding protein, IL18BPa
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M UREA, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Alternative Name
- IL18BP (IL18BP Products)
- Synonyms
- IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
- Background
- IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 20.0 kDa (187aa)
- NCBI Accession
- NP_001138529
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