KCTD11 Protein (His tag)
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- Target See all KCTD11 Proteins
- KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This KCTD11 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product KCTD11 Protein
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- Comment
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Synonyms: BTB/POZ domain-containing protein KCTD11, C17orf36, KCASH1, MGC129844, REN, REN/KCTD11
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))
- Alternative Name
- KCTD11 (KCTD11 Products)
- Synonyms
- KCTD11 Protein, AF465352 Protein, Ren Protein, C17orf36 Protein, KCASH1 Protein, REN Protein, REN/KCTD11 Protein, potassium channel tetramerization domain containing 11 Protein, potassium channel tetramerisation domain containing 11 Protein, KCTD11 Protein, Kctd11 Protein
- Background
- BTB/POZ domain-containing protein KCTD11, is a 232 amino acid regulator of neuronal differentiation that induces growth arrest, apoptosis and the expression of p27, a cyclin-dependent kinase inhibitor. Expressed at highest levels in cerebellum, KCTD11 functions as an antagonist of the Hedgehog pathway and activator of the caspase cascade. Recombinant human KCTD11 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 28 kDa (252aa)
- NCBI Accession
- NP_001002914
- Pathways
- Hedgehog Signaling
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