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IL-6 Protein

IL6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE analysis. BCA Active
Catalog No. ABIN1112348
  • Target See all IL-6 (IL6) Proteins
    IL-6 (IL6) (Interleukin 6 (IL6))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 32
    • 18
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 51
    • 24
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    Biochemical Assay (BCA)
    Sequence
    MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM.
    Characteristics
    The ED50 as determined by the dose-dependent stimulation of murine 7TD1 cells is less or equal to 0.1 µg/ml, corresponding to a Specific Activity of < 0.5x 108 IU/mg.
    Purity
    > 95 % as determined by SDS-PAGE analysis.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin: 1.EU/µg determined by LAL method.
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  • Comment

    Length: 185 AA

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommended that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Lyophilized hIL-6 should be reconstituted in deionized water to 0,1-1 µg/mL to regain full activity. These stock solutions should be apportioned into working aliquots and stored at -20 °C. Further dilutions should be made in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA.
    Storage
    -20 °C
  • Xin, Mizukami, Urabe, Toda, Shinoda, Yoshida, Oomura, Kojima, Ichino, Klinman, Ozawa, Okuda: "Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells." in: Journal of virology, Vol. 80, Issue 24, pp. 11899-910, (2006) (PubMed).

  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Alternative Name
    IL-6 (IL6 Products)
    Molecular Weight
    21 kDa
    Pathways
    TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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